Fierce clashes flared for a fourth day Tuesday in Syria's commercial capital of Aleppo, showing the resilience of a rebel assault on regime targets.

Pres. Obama warned Syria against using its chemical weapons after Damascus acknowledged for the first time on Monday that they possessed such weapons and threatened to use them against any "foreign aggression."

The state news agency said regime forces fought with rebels in the Aleppo neighborhoods of Salaheddine and Sukkari and claimed they had inflicted heavy losses. The Britain-based Syria Observatory, meanwhile, reported heavy fighting after midnight in several other neighborhoods as well as shelling by regime forces.

Some areas also saw protests calling for the fall of the government early in the morning, the Observatory reported.

On Sunday, a newly formed alliance of rebel groups called the Brigade for Unification announced an operation to liberate Aleppo, the country's largest city with about three million people.

Reports from opposition activists indicate the fighting has been restricted to certain outer neighborhoods and hasn't reached the city center. Monday online video though showed rebels disabling at least two regime tanks.

Damascus, which saw an even fiercer rebel assault last week, appears to be largely in government hands once more as government troops scoured neighborhoods for the remnants of rebel fighters, the state news agency reported.

Syria warned the international community Monday that it had chemical weapons and would use them in the case of any international aggression. The regime said it would not use them against its own people.

There had been fears that the embattled regime would use chemical weapons as a final desperate measure against the 17-month old rebellion. But the promise not to use them against Syrians was not entirely reassuring because officials have long characterized the rebels as foreign terrorists...

Syria has become increasingly isolated on the international stage, with just regional ally Iran in its corner, as well as Russia and China protecting it from condemnation by the U.N. Security Council.

Most of its neighbors, however, have become increasingly hostile, including regional powerhouse Turkey. At a political rally late Monday, Turkish Prime Minister Recep Erdogan predicted the imminent end of the regime.

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